The largest city in Kentucky, Louisville is made up of about 750,000 Americans. Today, Louisville is famous for their support of the thoroughbred horse breeding culture through the Kentucky Derby, Churchill Downs, and the Triple Crown overall. Locals of Louisville consider themselves as ͞Louisvillian͟and are influenced by southern and Midwestern American culture. Louisville is often referred to jokingly as either the southern-most northern city, or the northern-most southern city. The city of Louisville is located south of the Ohio River and southeast of the Falls of the Ohio. Louisville has an old-American feel to it, with modern skyscrapers adjacent to older and preserved structures. The Old Louisville neighborhood is the largest preservation district in America dedicated to Victorian homes and buildings. Louisville is an important hub for the shipping industry due to its location at the Falls of the Ohio, ranking as the seventh largest inland port in the US. Health care and medical science industry have emerged as important sectors of business in Louisville recently. Louisville is home to Fortune 100, 500, and 1000 companies such as Kindred Healthcare Incorporated, Brown-Forman Corp., PharMerica as well as other reputable companies like Papa John͛s Pizza and Hillerich & Bradsby, manufacturer of the famous Louisville Slugger baseball bats.